Speaking of Mol Bio

The genetics and neuroendocrinology of obesity

Episode Summary

We kick off Season 3 with Dr. Giles Yeo, a molecular neuroendocrinologist from the University of Cambridge, exploring the genetics behind obesity and its connection to brain function and feeding behavior. From insights into hormones like GLP-1 to cutting-edge genomic techniques, Dr. Yeo shares how his research is helping shape the future of personalized medicine and obesity treatments.

Episode Notes

Obesity is one of the most pressing health challenges of our time, with genetic and molecular factors playing a crucial role in how our bodies regulate weight. In this season opener, we explore the science behind obesity, focusing on how hormones, genetics, and brain circuits influence feeding behavior and body weight. Join us for a fascinating discussion about the interplay between molecular biology and real-world health outcomes.

Our guest, Dr. Giles Yeo, is a professor of molecular neuroendocrinology at the University of Cambridge and an expert in the genetics of obesity. With decades of research experience, Dr. Yeo dives into how hormones like GLP-1 interact with the brain and how genetic mutations can affect eating behaviors. He also explains the innovative molecular biology techniques his lab uses to map brain circuits and decode the genetic influences on body weight.

But this episode isn’t all about the lab. Dr. Yeo shares his journey from studying the genetics of Japanese pufferfish to becoming a leading voice in obesity research and science communication. Whether he’s decoding how Ozempic works or reflecting on the importance of good science communication, Dr. Yeo’s passion for the field—and his knack for making complex topics relatable—shines through.